Monday, October 15, 2018

Article Review


Articlee 1
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Wilson, SE, T Harris, P Sethi, J Fediurek, L Macdonald, and SL Deeks. "Coverage from Ontario, Canada'sSchool-Based Hpv Vaccine Program: the First Three Years."Vaccine. 31.5 (2013): 757-62. Print.
The objective of this program was in presenting a calculation of the provincial Vaccine coverage via the use of a survey that permitted the HIU to report the data they felt that it best reflected the local coverage. The rationale behind this was to assist in the examination of the sources of the denominator data that was employed in estimating the vaccine program’s target population as well as to obtain feedback on the local methods for HPV vaccine coverage evaluation.
Target Population
The program targets the grade eight girl students aged 13 years old. 36 health units administered the program in Ontario, which have a huge population of approximately 34,000 to 2.7 million. The schools collect and disseminate the locally developed informed consent forms and additionally provide the necessary facilities within the school for student vaccination.
Personnel
The individualized surveys were emailed every vaccination preventable disease manager working in any of Ontario's health units.
Setting
The program was implemented in a school setting whereby the nurse staff employed by the HUs administered the vaccine to the eligible students within the school setting.
The Program
The program was administered locally by the 36 HUs in Ontario. The HU staff input the data into the IRIS for updating the immunization status of the students receiving the HPV vaccine. The individualized surveys were emailed to each of the presentable vaccine managers in the 26 HUs in Ontario in March 2011. The content of the survey included the request for the coverage of the estimates for the three initial years of the program as well as questions in the denominator source.
The program did not use a theory as a premise from the evaluation
The Material
The material needed in during this program included the health units, the consent forms and appropriate facilities for the administration of the vaccine in schools.  The HPV vaccine is additionally vital to the program, with the HU staff and the participants being central to the success of the program.
Program Evaluation
Provincial denominator approximations were assessed from the survey via the summing of denominator data that was provided by the HUs across the 36 HUs for every program year. The provincial HPV vaccine coverage approximations were attained by dividing the summed numerator data via the summed denominator data for every program year. Data from HUs were combined to best estimate current provincial coverage. Coverage was computed based on the school-year throughout when the series was started, rather than completed. It was not imperative that students complete the sequence within a specified time to be considered complete. Chi-squared tests were additionally adopted in comparing the coverage estimates between as well as within data sources for every program year moreover to evaluate the proportion of HUs who reported on coverage with extended eligibility over time.
An advantage of the program was able to establish the basis for the coverage of the HPV vaccine, making clear the issues that should be addressed to promote greater coverage in the administration of the vaccine.  The main limitation is that the fact that the program is grade based and not aged based, the calculation of target population is complex, increasing the risk of overlooking the deserving candidates.
Article 2
Trottier, H., Mayrand, M.-H., CoutlĂ©e, F., Monnier, P., Laporte, L., Niyibizi, J., Carceller, A.-M., ... Audibert, F. (December 01, 2016). Human papillomavirus (HPV) perinatal transmission and risk of HPV persistence among children: Design, methods and preliminary results of the HERITAGE study. Papillomavirus Research, 2, 145-152.
The objective of the article is in the assessment of the Route for the transmission route in perinatal for human papillomavirus (HPV). In this program, attempts are made towards the advancing of the comprehension of the rate along with determinants of perinatal transmission and rate along with determinants of the persistence of HPV in children. The program desires to present the study design as well as offer preliminary data from the large prospective cohort study relating to the perinatal transmission of HPV.
Target Population
The heritage involved the recruitment of women in academic hospitals along with the high volume of obstetrical units in Montreal Canada. In each of the hospitals, the participants were recruited in the outpatient obstetric clinics catering for the local community. In this case, pregnant women were accrued in the initial phase of the study that occurred from 2010 to June 2012. The pregnant women over the age of 18 years, as well as those between 6 and 14 weeks of gestation, were enrolled for the heritage study. The participants’ children who were positive for HPV DNA in the first trimester were followed until they got to 2 years of age.
Personnel
The program used nurses and research staff, who received training about the collection of samples from the research participants.
Setting
The program was implemented in the diverse academic hospitals as well as obstetrical units in Montreal Canada. The recruitment for the HERITAGE was conducted in 3 teaching hospitals in Montreal as a subsample of the 3D study.
The Program
In the initial visit, a self-collected cervicovaginal specimen that was obtained via the use of a dry Dacron swap that was obtained from pregnant mothers for the type-specific HPV DNA testing. The research staff, as well as the nurses, was trained for the collection of the samples in the children and children participants. They additionally were trained to disclose as well as explain the HPV DNA tests results. The study protocol was further approved by the institutional ethical as well as research review boards concerned with the participating institutions.
The implementation of the program was not based upon any theoretical premises.
The program used self-collected cervicovaginal specimen via the use of a dry Dacron swab for specific testing of HPV DNA. Further, there was the use of placenta brush as well as biopsy were used in collecting HPV DNA testing on both the maternal as well as the fetal side in each participant. Two catalog brushes were adopted in collecting cells from peripheral as well as central zones. Virox was employed in cleaning scissors, clamps and any other tool used. Gloves were also used in the procedure, with liquid preservatives being used during the storage of specimens. Questionnaires were used in documenting the social-demographic data as well as pre-birth indicators of the participants.
Program Evaluation
The pregnant women who were recruited in the first trimester provided their HPV DNA samples at the first trimester, while placenta samples were provided after birth. DNA testing was additionally repeated in during the third trimester for the participants who had tested positive in the first trimester, with the children of the women who tested positive followed till they were two years old.
Some of the pros of the program as that it offers the picture of the risks factors lined with the perinatal transmission thus making it possible for the stakeholders in healthcare to develop strategies to aid in dealing with the challenge. However, the fact that it does not offer an explanation of the consequences of HPV infections on the pregnant women is a disadvantage of the study. The study further fails to enumerate a comprehensive understanding of the mechanism that can be adopted in the assessment of the transmission from the mother to the child, making it hard to address the transmission issue.
Sherry Roberts is the author of this paper. A senior editor at Melda Research in nursing paper writing services if you need a similar paper you can place your order for medical essay writing service online.




                                                                                                       


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